产品货号:
Z31852
中文名称:
CD46抗体
英文名称:
Anti-CD46 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD46 Antibody |
指标别名 | CD46;MCP;Membrane cofactor protein;MIC10;TLX;TRA2.10 |
克隆性 | Monoclonal |
检验物种 | human,rabbit |
应用范围 | WB,IHC,ICC/IF |
基因名称 | CD46 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human CD46 |
实际分子量 | 50~70KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene.The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system.And the encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I,which protects the host cell from damage by complement.In addition,the encoded protein can act as a receptor for the Edmonston strain of measles virus,human herpesvirus-6,and type IV pili of pathogenic Neisseria.Finally,the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome.Alternatively spliced transcript variants encoding different isoforms have been described. |
Uniprot ID | P15529 |
基因名全称 | Membrane cofactor protein |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
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